It is been considered for many years that Men with Heart Failure should avoid from taking hormone treatments like HGH Therapy and especially Testosterone Therapy. But from current studies it is been observed that testosterone supplementation is useful for both patients with low and normal testosterone levels, although the improvements are greater in those with low levels. This was observed by “Dr. Ferdinando Iellamo”, an assistant professor of internal medicine at the University of Rome Tor Vergata, and lead author of a report in the Sept. 1 issue of the Journal of the American College of Cardiology.
The Italian study included 70 elderly men with heart failure, all of whom had low testosterone levels. All received standard heart failure therapy, but half also received injections of 1,000 milligrams of long-acting testosterone at the start, and again at six and 12 weeks. A series of examinations â€” electrocardiograms, exercise tests and assessments of muscle strength â€” showed improvements in the men who received the hormone replacement therapy treatment but not in those who didn’t.
It’s not possible to specify the timing and dosage of testosterone therapy for men with heart failure, Iellamo said.
“There is no current guideline,” he said. “However, our study indicates that long-acting testosterone at the dose and intervals we employed [to date used only in patients with hypogonadism] is safe and well-tolerated in patients with heart failure.”
The study was not designed to determine whether testosterone therapy would prolong survival of men with heart failure, Iellamo said. “Future large trials are needed to appropriately evaluate the outcome,” he said.
Men with heart failure who are tempted to try testosterone therapy on their own should avoid the temptation, he said. “It is absolutely contraindicated that patients choose testosterone, as well as all drugs, on their own,” Iellamo said. The warning is especially important for men with high levels of prostate-specific antigen, an indicator of prostate cancer risk, he noted.
“This study confirms our previous finding for a beneficial effect of testosterone in men with moderate chronic heart failure, improving functional exercise capacity and insulin resistance,” said Dr. T. Hugh Jones, a consultant endocrinologist at the University of Sheffield in England.
ones and his colleagues have reported two studies with positive results, one using testosterone injections, the other using a hormone-delivering skin patch.
“Historically, testosterone replacement therapy has been contraindicated in men with chronic heart failure,” Jones said. “This was due to the fluid retention observed with older forms of testosterone preparation. This study, along with our studies, show that testosterone is safe in these patients and has a benefit on the underlying condition.”
But the case for testosterone therapy in heart failure is far from proven, he said. “Now, longer-term studies evaluating effects on survival, quality of life and longer-term safety need to be done to establish if this treatment should be used routinely in the treatment of heart failure in men,” Jones said.
Jones also told that case for testosterone therapy in heart failure is far from proven. He also said that studies shows longer-term survival, quality of life and longer-term safety need to be done to establish if this treatment should be used routinely in the treatment of heart failure in men.
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